Examining adaptations of a dominant bacterial species at a contaminated subsurface site - Leveraging comparative genomics, community analysis, and geochemical data to understand adaptations that facilitate survival of a dominant community member in the contaminated Oak Ridge Reservation subsurface. News Article →
ENIGMA researchers identify hundreds of new enzymes - Filling Gaps in Bacterial Metabolism with Computation and High-throughput Genetics: An analysis of genetic data from many different kinds of bacteria identified hundreds of new enzymes. News Article →
The Contextual Ontology-based Repository Analysis Library (CORAL) facilitates FAIR ENIGMA datasets - Novichkov, PS*; Chandonia, J-M*; Arkin, AP. (2022) CORAL: A framework for rigorous self-validated data modeling and integrative, reproducible data analysis. GigaScience [DOI]:10.1093/gigascience/giac089 OSTI ID: 1888047 The Contextual Ontology-based Repository Analysis Library (CORAL) platform greatly facilitates adherence to the FAIR principles, including the especially difficult challenge of making… News Article →
2022 Soil Science Research Award - Jizhong Joe Zhou ENIGMA Principal Investigator at University of Oklahoma Norman was inducted into the Soil Science Society of America Awards Hall of Fame. It is a great honor to receive 2022 SSSA Award, which recognizes outstanding research contributions in soil science. Some of his research related to… News Article →
ISME-IWA BioCluster Grand Prize Award 2022 - ENIGMA Principal Investigator Jizhong Joe Zhou received the prestigious ISME-IWA BioCluster Grand Prize Award 2022. The ENIGMA-supported research related to groundwater microbiomes as well as ecological theories (e.g. stochastic processes) constitute the main body of work considered for this grand Prize. This prestigious prize rewards interdisciplinary research of… News Article →
Using microcalorimetry and thermodynamic modeling to examine effects of thermal stress - Hunt KA, von Netzer F, Gorman-Lewis D, Stahl DA. (2022) Microbial maintenance energy quantified and modeled with microcalorimetry. Biotechnol Bioeng. 2022 Jun 9; [DOI]:10.1002/bit.28155. {PMID}: 35680566 OSTI:1874049 All known biology is driven by the partitioning of energy released from nutrient consumption, either into building new cells or maintaining… News Article →
Discovering microbial adaptations to subsurface niches - Gushgari-Doyle, S; L.M. Lui, T.N. Nielsen, X. Wu, R.G. Malana, F.L. Poole II, M.W.W. Adams, A.P. Arkin, R. Chakraborty (2022) Genotype to ecotype in niche environments: Adaptation of Arthrobacter to carbon availability and environmental conditions. ISME Comm. [DOI]:10.1038/s43705-022-00113-8 OSTI:1860268 Different niche micro-environments can affect the structure and function… News Article →
ENIGMA science engages undergraduate researcher in environmental microbiology - University of Georgia undergraduate student Elizabeth Szink has been working in the lab of ENIGMA principal investigator Mike Adams under the guidance of ENIGMA postdoctoral researcher Jennifer Goff. News Article →
Whole genome sequence reveals molecular mechanisms underlying adaptation of Rhodanobacter strains to multiple stressors - The Genomic Features Underlying Adaptation of Rhodanobacter Strains to Stressful Conditions (denitrification processes, heavy metal resistance, and restriction-modification systems) present at ENIGMA Field Site ORR. Rhodanobacter species have been found dominant in the subsurface of Oak Ridge Reservation (ORR) site contaminated with acid, nitrate, metal radionuclides, and other… News Article →
Sampling Down Well In Situ Microbial Colonization Conditions - LJ McKay*, HJ Smith*, E Barnhart, HD Schweitzer, RR Malmstrom, D Goudeau, MW Fields (2021) Activity-based, genome-resolved metagenomics uncovers key populations and pathways involved in subsurface conversions of coal to methane Nature ISME Journal [DOI]:10.1038/s41396-021-01139-x PMID: 34689183 Development of activity-based metagenomics, enabled the identification of translationally active microorganisms and… News Article →
Uncovering metal tolerance mechanisms using ENIGMA tools and Analysis - Thorgersen, M.P., .; J. Xue, E.L.W. Majumder, V.V. Trotter, X. Ge, F.L. Poole II, T.K. Owens, L.M. Lui, T.N. Nielsen, A.P. Arkin, A.M. Deutschbauer, G. Siuzdak, and M.W.W. Adams Deciphering microbial metal toxicity responses using RB-TnSeq and activity-based metabolomics. Applied and Environmental Microbiology 87 (21), e01037-21 (2021).… News Article →
Observing the Microbial Genome - Basics2Breakthroughs: Observing the microbial genome from Berkeley Lab on YouTube. ENIGMA Project Scientist Lauren Lui is profiled on LBL Basics2Breakthroughs, filmed for LBNL's 90th anniversary. She uses the latest bioinformatics technology to study microbes so we can learn how their genes shape the environment. Her ultimate goal is… News Article →