Berkeley Lab

Rapidly Moving New Bacteria to Model Organism Status

ENIGMA researchers describe our proposed workflow as a general guideline for studying new environmental microbes in a fast and comprehensive way.

Liu, H.; A.M. Deutschbauer (2018) Rapidly moving new bacteria to model‐organism status. Current Opinion in Biotechnology. DOI: 10.1016/j.copbio.2017.12.006

Currently there is a need to rapidly move new bacteria to “model organism” status, given the importance of a diverse range of these microorganisms to human health, the environment, and biotechnology. Hualan Liu proposes at a minimum, a new model bacterium should have a complete and accurately annotated genome, tools for genetic manipulation, and a computational framework for data analysis. ENIGMA  now has a number of tools available to accelerate the development of a new model bacterium, aided by advances in next-generation sequencing, functional genomics, and shared computational platforms for systems biology