Berkeley Lab

Key Cellular Components Persist in Bacteria Although Response to Salt Stress Changes

ENIGMA researchers at University of Oklahoma, Lawrence Berkeley Lab, University of Washington, and University of Missouri reveal that the accumulation and induction of key cellular components persists in bacteria for greater than 5000 generations although the physiological and transcriptional responses to high salinity is altered. The mechanistic changes in evolved genotypes suggested that growth energy efficiency might […]

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Metabolizing Data in the Cloud

ENIGMA researchers at Scripps Research Institute have developed tools with available data to enable microbial and environmental research. ENIGMA’s XCMS Online systems biology data processing and the METLIN database represent a successful model of how community oriented cloud-computing can be implemented on a global scale. This free, cloud-based platform provides users with processing tools, data streaming, […]

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Benchmark properties for highly accurate bacterial protein interactions

SUMMARY Numerous affinity purification – mass-spectrometry (AP-MS) and yeast two hybrid (Y2H) screens have each defined thousands of pairwise protein-protein interactions (PPIs), most between functionally unrelated proteins. The accuracy of these networks, however, is under debate. Here we present an AP-MS survey of the bacterium Desulfovibrio vulgaris together with a critical reanalysis of nine published […]

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Metallomics of Two Microorganisms Featured on Metallomics Blog

Metallomics of Two Microorganisms Relevant to Heavy Metal Bioremediation Reveal Fundamental Differences in Metal Assimilation and Utilization was selected as a Hot Article and featured on the Metallomics blog.

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Barcoded Transposon Mutant Library

A D. vulgaris Hildenborough barcoded transposon mutant library →

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Functional Gene Array Design and Microarray Data

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